A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Nanotechnology gives A selection of prospects to add to biology. In this article I will present examples in which nanofabrication – the opportunity to make confined constructions with Proportions at will – is applied to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
Our team experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
[Laughs] ‘It had been undoubtedly a fantastic threat! At the time, I was well knowledgeable that it could go Completely wrong Which I could develop into significantly less prosperous, but I just overlooked that. Curiosity has often been my strongest driving power. And luckily it all labored out.’
Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2010, produced a whole new way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We form microorganisms into types that deviate from their all-natural phenotype. Particularly, I'll exhibit our capacity to form live E. coli microbes into novel styles for example rectangles, squares, triangles and circles.
2000, discovery that nanotubes can have extraordinary huge present-day densities; resolved the controversial situation of Digital transport by means of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes
Understanding fundamental procedures regulating the spatial and dynamic organisation of your DNA in Are living cells.
Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro
Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion from roadblock-traversal experiments
1999, to start with measurement on the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for your new Luttinger description of interacting electrons in nanotubes
2005, discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of extensive-assortment conformational variations in Mre11/DNA fix complexes; and to start with power measurements over a DNA molecule in a nanopore
‘I am driven by ponder and thoughts. On a material level I locate solutions in physics, but I practical experience my deepest contentment with God. That religion also drives my science https://www.ceesdekker.net and how I cope with men and women.